Pub. Date : 2014 Sep
PMID : 25202056
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Expression of ABCB6 is related to resistance to 5-FU, SN-38 and vincristine. | Fluorouracil | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
2 | ABCB6 expression enhanced resistance to 5-fluorouracil (5-FU), SN-38 and vincristine (Vcr) but not to arsenite. | Fluorouracil | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
3 | ABCB6 expression enhanced resistance to 5-fluorouracil (5-FU), SN-38 and vincristine (Vcr) but not to arsenite. | Fluorouracil | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
4 | Conversely, down-regulation of ABCB6 in KAS cells increased the sensitivity of KAS cells to 5-FU, SN-38 and Vcr, but not to arsenite. | Fluorouracil | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
5 | Our findings suggest that ABCB6 is involved in 5-FU, SN-38 and Vcr resistance. | Fluorouracil | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |