Title : Methadone is a non-competitive antagonist at the α4β2 and α3* nicotinic acetylcholine receptors and an agonist at the α7 nicotinic acetylcholine receptor.

Pub. Date : 2015 Apr

PMID : 25196810






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The Ki values for methadone were 6.3 muM in SH-EP1-halpha7 cells and 19.4 muM and 1008 muM in SH-SY5Y cells. Methadone latexin Homo sapiens
2 The Ki values for methadone were 6.3 muM in SH-EP1-halpha7 cells and 19.4 muM and 1008 muM in SH-SY5Y cells. Methadone latexin Homo sapiens
3 The Ki values for methadone were 6.3 muM in SH-EP1-halpha7 cells and 19.4 muM and 1008 muM in SH-SY5Y cells. Methadone latexin Homo sapiens