Title : Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering.

Pub. Date : 2014 Oct 9

PMID : 25191794






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 DM1 is an analog of the natural product maytansine, a microtubule inhibitor that by itself has limited clinical activity and high systemic toxicity. Maytansine immunoglobulin heavy diversity 1-7 Homo sapiens