Title : Assessment of intraoral mucosal pain induced by the application of capsaicin.

Pub. Date : 2014 Dec

PMID : 25189505






4 Functional Relationships(s)
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1 The number of c-Fos protein-like immunoreactive (Fos-LI) neurons in the medullary dorsal horn (MDH) induced by the intraoral application of capsaicin was measured. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 RESULTS: Larger doses of intraoral capsaicin (1, 10 and 100mug) induced vigorous licking behaviour and c-Fos response in the MDH in a reproducible manner. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 The magnitudes of both behavioural activity and the c-Fos response from the 10 and 100mug doses of capsaicin were significantly greater than that by the 1mug dose. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
4 Injury to the IAN exaggerated the behavioural and c-Fos responses evoked by intraoral capsaicin. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus