Pub. Date : 2014 Sep
PMID : 25185187
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SUMMARY: In this issue of Cancer Discovery, AI-Ahmadie and colleagues identify a somatic mutation in the RAD50 gene as a likely contributing factor to an unusual curative response to systemic combination therapy employing the DNA-damaging agent irinotecan and a checkpoint kinase 1 inhibitor in a patient with recurrent, metastatic small-cell cancer. | Irinotecan | RAD50 double strand break repair protein | Homo sapiens |