Pub. Date : 2014 Mar
PMID : 25182442
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: To evaluate of hesperidin to overcome resistance of doxorubicin in MCF-7 resistant doxorubicin cells (MCF-7/Dox) in cytotoxicity apoptosis and P-glycoprotein (Pgp) expression in combination with doxorubicin. | Hesperidin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | OBJECTIVE: To evaluate of hesperidin to overcome resistance of doxorubicin in MCF-7 resistant doxorubicin cells (MCF-7/Dox) in cytotoxicity apoptosis and P-glycoprotein (Pgp) expression in combination with doxorubicin. | Hesperidin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Hesperidin did not increase the apoptotic induction, but decreased the Pgp expressions level when combined with doxorubicin in low concentration. | Hesperidin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Co-chemotherapy application of doxorubicin and hesperidin on MCF-7/Dox cells showed synergism effect through inhibition of Pgp expression. | Hesperidin | ATP binding cassette subfamily B member 1 | Homo sapiens |