Title : N-formylpyrazolines and N-benzoylpyrazolines as novel inhibitors of mammalian cathepsin B and cathepsin H.

Pub. Date : 2014 Dec

PMID : 25181676






1 Functional Relationships(s)
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Protein Name
Organism
1 The most potent inhibitors among the two series were nitro substituted compounds 1i and 2i with Ki values of ~1.1x10(-9)M and 19.5x10(-8)M for cathepsin B and Ki values of ~5.19x10(-8)M and 9.8x10(-7)M for cathepsin H, respectively. nitro cathepsin B Homo sapiens