Title : Inhibition of the MDM2 E3 Ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with ABT-737.

Pub. Date : 2014

PMID : 25181509






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 When MI-63 was combined with the BH3 mimetic ABT-737, enhanced activity was seen in both wild-type and mutant p53 models. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid tumor protein p53 Homo sapiens