Title : E2F1 downregulation by arsenic trioxide in lung adenocarcinoma.

Pub. Date : 2014 Nov

PMID : 25174355






1 Functional Relationships(s)
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1 Treatment with ATO resulted in phosphatidylserine externalization in H23 cells and mitochondrial membrane depolarization in all cell lines, associated with truncation of Bid, downregulation of Bcl-2, upregulation of Bax and Bak, caspase-9 and -3 activation and PARP cleavage. Arsenic Trioxide BCL2 associated X, apoptosis regulator Homo sapiens