Title : HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin.

Pub. Date : 2014 Oct 17

PMID : 25170080






2 Functional Relationships(s)
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1 However, the effects of calnexin knockdown and Nef on cholesterol efflux were not additive; in fact, the combined effect of these two factors together did not differ significantly from the effect of calnexin knockdown alone. Cholesterol S100 calcium binding protein B Homo sapiens
2 This study identifies a mechanism for Nef-dependent inactivation of ABCA1 and dysregulation of cholesterol metabolism. Cholesterol S100 calcium binding protein B Homo sapiens