Title : Comparison of the effects of betamethasone and dexamethasone on surfactant protein A mRNA expression in human lung cells.

Pub. Date : 2015 Jul

PMID : 25162121






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1 Comparison of the effects of betamethasone and dexamethasone on surfactant protein A mRNA expression in human lung cells. Dexamethasone surfactant protein A1 Homo sapiens
2 We compared the dose-dependent effects of various concentrations of two synthetic corticosteroids, betamethasone and dexamethasone, on steady state levels of surfactant protein A (SP-A) mRNA in human lung cells. Dexamethasone surfactant protein A1 Homo sapiens
3 We compared the dose-dependent effects of various concentrations of two synthetic corticosteroids, betamethasone and dexamethasone, on steady state levels of surfactant protein A (SP-A) mRNA in human lung cells. Dexamethasone surfactant protein A1 Homo sapiens
4 RESULTS: A dose-dependent modification in SP-A mRNA levels was demonstrated with both dexamethasone and betamethasone. Dexamethasone surfactant protein A1 Homo sapiens
5 At higher corticosteroid concentrations, betamethasone is less inhibitory than dexamethasone on SP-A mRNA. Dexamethasone surfactant protein A1 Homo sapiens