Title : Electrogenerated chemiluminescence aptasensor for ultrasensitive detection of thrombin incorporating an auxiliary probe.

Pub. Date : 2014 Dec

PMID : 25159423






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A novel electrogenerated chemiluminescence (ECL) aptasensor for ultrasensitive detection of thrombin incorporating an auxiliary probe was designed by employing specific anti-thrombin aptamer as a capture probe and a ruthenium(II) complex-tagged reporter probe as an ECL probe and an auxiliary probe to assist the ECL probe close to the surface of the electrode. Ruthenium(II) coagulation factor II, thrombin Homo sapiens
2 When analyte thrombin was bound with the capture probe, the part of the dehybridized ECL probe was hybridized with the neighboring auxiliary probe, led to the tagged ruthenium(II) complex close to the electrode surface, resulted in great increase in the ECL intensity. Ruthenium(II) coagulation factor II, thrombin Homo sapiens