Pub. Date : 2014 Dec
PMID : 25159423
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | A novel electrogenerated chemiluminescence (ECL) aptasensor for ultrasensitive detection of thrombin incorporating an auxiliary probe was designed by employing specific anti-thrombin aptamer as a capture probe and a ruthenium(II) complex-tagged reporter probe as an ECL probe and an auxiliary probe to assist the ECL probe close to the surface of the electrode. | Ruthenium(II) | coagulation factor II, thrombin | Homo sapiens |
2 | When analyte thrombin was bound with the capture probe, the part of the dehybridized ECL probe was hybridized with the neighboring auxiliary probe, led to the tagged ruthenium(II) complex close to the electrode surface, resulted in great increase in the ECL intensity. | Ruthenium(II) | coagulation factor II, thrombin | Homo sapiens |