Title : Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.

Pub. Date : 2014 Nov

PMID : 25156145






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 JNK signaling led to Bcl-xL phosphorylation at serine 62, dissociation of Bak from Bcl-xL, oligomerization of Bak, alteration of mitochondrial membrane potential, and subsequent cytochrome c release. Serine mitogen-activated protein kinase 8 Homo sapiens