Pub. Date : 1989 May
PMID : 2514051
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UNLABELLED: To investigate the mechanism by which clonidine stimulates GH-secretion in vivo and in vitro, we studied its interaction with GHRH. | Clonidine | growth hormone releasing hormone | Rattus norvegicus |
| 2 | The GHRH bolus after clonidine led to a significantly lower GH-increase (max 31.6 +/- 17.0 mU/l) compared to the GHRH-induced GH-increase (max 47.2 +/- 13.0 mU/l) before clonidine. | Clonidine | growth hormone releasing hormone | Rattus norvegicus |
| 3 | The GHRH bolus after clonidine led to a significantly lower GH-increase (max 31.6 +/- 17.0 mU/l) compared to the GHRH-induced GH-increase (max 47.2 +/- 13.0 mU/l) before clonidine. | Clonidine | growth hormone releasing hormone | Rattus norvegicus |
| 4 | These findings are compatible with clonidine leading to stimulation of GH by inducing endogenous GHRH release. | Clonidine | growth hormone releasing hormone | Rattus norvegicus |