Title : Phospholipase A2 regulates eicosanoid class switching during inflammasome activation.

Pub. Date : 2014 Sep 2

PMID : 25139986






1 Functional Relationships(s)
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1 Initial activation of TLR4 results in accumulation of the cyclooxygenase-2-derived lipoxin precursor 15-hydroxyeicosatetraenoic acid (15-HETE) in esterified form within membrane phospholipids, which can be enhanced by aspirin (ASA) treatment. Eicosatetraenoic acid, 15-hydroxy- prostaglandin-endoperoxide synthase 2 Homo sapiens