Title : Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse.

Pub. Date : 2014 Aug 19

PMID : 25139304






2 Functional Relationships(s)
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1 This study investigates, whether pharmacologic acetylcholinesterase inhibition with neostigmine diminishes liver damage in acute liver failure via the cholinergic anti-inflammatory pathway. Neostigmine acetylcholinesterase Mus musculus
2 CONCLUSIONS: Neostigmine is an acetylcholinesterase inhibitor that ameliorates the effects of APAP-induced acute liver failure in the mouse and therefore may provide new treatment options for affected patients. Neostigmine acetylcholinesterase Mus musculus