Pub. Date : 1989 Nov
PMID : 2513480
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | beta-Galactosidase activity in yeast strains containing the RNR2-lacZ fusion was inducible in response to DNA-damaging agents (UV light, 4-nitroquinoline-1-oxide [4-NQO], and methyl methanesulfonate [MMS]) and agents that block DNA replication (hydroxyurea [HU] and methotrexate) but not heat shock. | Methyl Methanesulfonate | ribonucleotide-diphosphate reductase subunit RNR2 | Saccharomyces cerevisiae S288C |
| 2 | beta-Galactosidase activity in yeast strains containing the RNR2-lacZ fusion was inducible in response to DNA-damaging agents (UV light, 4-nitroquinoline-1-oxide [4-NQO], and methyl methanesulfonate [MMS]) and agents that block DNA replication (hydroxyurea [HU] and methotrexate) but not heat shock. | Methyl Methanesulfonate | ribonucleotide-diphosphate reductase subunit RNR2 | Saccharomyces cerevisiae S288C |
| 3 | A mutation, rnr2-314, was found to confer hypersensitivity to HU and increased sensitivity to MMS. | Methyl Methanesulfonate | ribonucleotide-diphosphate reductase subunit RNR2 | Saccharomyces cerevisiae S288C |