Title : Modulation of growth gene expression by selective alteration of polyamines in human colon carcinoma cells.

Pub. Date : 1989 Nov 30

PMID : 2511847






1 Functional Relationships(s)
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1 Our previous studies have shown that generalized polyamine depletion of the human colon cancer cell line COLO 320 by 2-difluoromethylornithine is associated with decreased transcription of the c-myc, c-fos, and ornithine decarboxylase (ODC) genes. Eflornithine MYC proto-oncogene, bHLH transcription factor Homo sapiens