Pub. Date : 2014
PMID : 25115845
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Targeting catalase but not peroxiredoxins enhances arsenic trioxide-induced apoptosis in K562 cells. | Arsenic Trioxide | catalase | Homo sapiens |
| 2 | We further investigated the possible role of peroxirdoxin 1/2/6 and catalase in determining the cellular sensitivity to As2O3. | Arsenic Trioxide | catalase | Homo sapiens |
| 3 | On the contrary, knockdown of catalase markedly enhanced As2O3-induced apoptosis. | Arsenic Trioxide | catalase | Homo sapiens |
| 4 | The current study reveals that the functional role of antioxidant enzymes is cellular context and treatment agents dependent; targeting catalase may represent a novel strategy to improve the efficacy of As2O3 in CML treatment. | Arsenic Trioxide | catalase | Homo sapiens |