Title : Impact of CYP2D*6 in the adjuvant treatment of breast cancer patients with tamoxifen.

Pub. Date : 2014 Aug 10

PMID : 25114852






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Biotransformation of tamoxifen to the potent antiestrogen endoxifen is performed by cytochrome P450 (CYP) enzymes, in particular the CYP2D6 isoform. 4-hydroxy-N-desmethyltamoxifen cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Biotransformation of tamoxifen to the potent antiestrogen endoxifen is performed by cytochrome P450 (CYP) enzymes, in particular the CYP2D6 isoform. 4-hydroxy-N-desmethyltamoxifen cytochrome P450 family 4 subfamily F member 3 Homo sapiens