Title : Helicobacter pylori promotes VEGF expression via the p38 MAPK‑mediated COX‑2‑PGE2 pathway in MKN45 cells.

Pub. Date : 2014 Oct

PMID : 25110109






4 Functional Relationships(s)
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Protein Name
Organism
1 Helicobacter pylori promotes VEGF expression via the p38 MAPK-mediated COX-2-PGE2 pathway in MKN45 cells. Dinoprostone vascular endothelial growth factor A Homo sapiens
2 It was also found that prostaglandin E2 (PGE2) and its receptor EP2/EP4 may mediate the upregulation of VEGF in gastric cells exposed to H. pylori. Dinoprostone vascular endothelial growth factor A Homo sapiens
3 It was also found that prostaglandin E2 (PGE2) and its receptor EP2/EP4 may mediate the upregulation of VEGF in gastric cells exposed to H. pylori. Dinoprostone vascular endothelial growth factor A Homo sapiens
4 In combination, these results suggest that VEGF expression is regulated by the p38 MAPK COX-2-PGE2-EP2/EP4 pathway in gastric cancer cells induced by H. pylori. Dinoprostone vascular endothelial growth factor A Homo sapiens