Title : Protective effects of glucose-6-phosphate dehydrogenase on neurotoxicity of aluminium applied into the CA1 sector of rat hippocampus.

Pub. Date : 2014 Jun

PMID : 25109721






3 Functional Relationships(s)
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1 G6PDH administered prior to AlCl 3 resulted in a reversal of the effects of AlCl3 on both biochemical and behavioural parameters. Aluminum Chloride glucose-6-phosphate dehydrogenase Rattus norvegicus
2 G6PDH administered prior to AlCl 3 resulted in a reversal of the effects of AlCl3 on both biochemical and behavioural parameters. Aluminum Chloride glucose-6-phosphate dehydrogenase Rattus norvegicus
3 INTERPRETATION & CONCLUSIONS: Our findings indicated that the G6PDH alleviated the signs of behavioural and biochemical effects of AlCl3-treatment suggesting its involvement in the pathogenesis of Al neurotoxicity and its potential therapeutic benefit. Aluminum Chloride glucose-6-phosphate dehydrogenase Rattus norvegicus