Pub. Date : 2014 Sep 26
PMID : 25096579
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Altered thiol chemistry in human amyotrophic lateral sclerosis-linked mutants of superoxide dismutase 1. | Sulfhydryl Compounds | superoxide dismutase 1 | Homo sapiens |
| 2 | In human SOD1 (hSOD1), a conserved disulfide bond and two free cysteine residues can engage in anomalous thiol/disulfide exchange resulting in non-native disulfides, a hallmark of ALS that is related to protein misfolding and aggregation. | Sulfhydryl Compounds | superoxide dismutase 1 | Homo sapiens |
| 3 | In human SOD1 (hSOD1), a conserved disulfide bond and two free cysteine residues can engage in anomalous thiol/disulfide exchange resulting in non-native disulfides, a hallmark of ALS that is related to protein misfolding and aggregation. | Sulfhydryl Compounds | superoxide dismutase 1 | Homo sapiens |