Pub. Date : 2014 Nov
PMID : 25096061
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Transcriptional regulation of STAT3 by SPTBN1 and SMAD3 in HCC through cAMP-response element-binding proteins ATF3 and CREB2. | Cyclic AMP | SMAD family member 3 | Homo sapiens |
2 | We also found that inhibition of SPTBN1 or SMAD3 upregulated STAT3 promoter activity in HCC cell-lines, which is dependent upon the cAMP-response element (CRE) and STAT-binding element (SBE) sites of the STAT3 promoter. | Cyclic AMP | SMAD family member 3 | Homo sapiens |