Title : Activation of CB1 inhibits NGF-induced sensitization of TRPV1 in adult mouse afferent neurons.

Pub. Date : 2014 Sep 26

PMID : 25088915






1 Functional Relationships(s)
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1 We found that CB1, NGF receptor tyrosine kinase A (trkA), and TRPV1 are present in cultured adult mouse small- to medium-sized afferent neurons and treatment with NGF (100ng/ml) for 30 min significantly increased the number of neurons that responded to capsaicin (as indicated by increased intracellular Ca(2 +) concentration). Capsaicin cannabinoid receptor 1 (brain) Mus musculus