Title : Direct activating effects of adrenocorticotropic hormone (ACTH) on brown adipose tissue are attenuated by corticosterone.

Pub. Date : 2014 Nov

PMID : 25085924






1 Functional Relationships(s)
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1 In T37i cells, ACTH dose-dependently increased Ucp1 mRNA (EC50=1.8 nM) but also induced Ucp1 protein content 88% (P=0.02), glycerol release 32% (P=0.03) and uncoupled respiration 40% (P=0.003). Glycerol pro-opiomelanocortin-alpha Mus musculus