Title : Cyclosporine-inhibitable cerebral drug transport does not influence clinical methadone pharmacodynamics.

Pub. Date : 2014 Dec

PMID : 25072223






2 Functional Relationships(s)
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Protein Name
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1 In vitro and animal studies suggest that methadone is a substrate for the efflux transporter P-glycoprotein, and that P-glycoprotein-mediated transport influences brain access and pharmacologic effect. Methadone ATP binding cassette subfamily B member 1 Homo sapiens
2 In vitro and animal studies suggest that methadone is a substrate for the efflux transporter P-glycoprotein, and that P-glycoprotein-mediated transport influences brain access and pharmacologic effect. Methadone ATP binding cassette subfamily B member 1 Homo sapiens