Title : Valproic acid attenuates the suppression of acetyl histone H3 and CREB activity in an inducible cell model of Machado-Joseph disease.

Pub. Date : 2014 Nov

PMID : 25068645






1 Functional Relationships(s)
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1 The expression of acetyl histone H3 and the induction of c-Fos in response to cAMP were strongly suppressed in cells expressing the protein with the expanded polyglutamine tract. polyglutamine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens