Title : Nitric oxide formation during microsomal hepatic denitration of glyceryl trinitrate: involvement of cytochrome P-450.

Pub. Date : 1989 Sep 29

PMID : 2506859






1 Functional Relationships(s)
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1 These data demonstrate that microsomal reductive denitration of glyceryl trinitrate is catalyzed by cytochrome P-450 and can be involved in the formation of the endothelium-derived relaxing factor (EDRF = nitric oxide). Nitroglycerin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus