Title : Effects of monoamine oxidase inhibitors on levels of catechols and homovanillic acid in striatum and plasma.

Pub. Date : 1989 Aug

PMID : 2506486






1 Functional Relationships(s)
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1 The results suggest that most of the HVA in plasma is derived from deamination of DA by MAO-A in peripheral neurons; that DOPAC in plasma is derived from cells outside the central nervous system; that DHPG in plasma is derived virtually exclusively from the metabolism of norepinephrine in sympathetic nerve endings and that residual levels of HVA after treatment with debrisoquin provide an improved but limited indication of central dopaminergic activity. amsonic acid monoamine oxidase A Homo sapiens