Pub. Date : 2014 Aug 25
PMID : 25064843
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phospholipase D2 downregulation induces cellular senescence through a reactive oxygen species-p53-p21Cip1/WAF1 pathway. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 2 | Taken together, these results show that PLD2 downregulation causes senescence through the p53-p21(Cip1/WAF1) pathway by stimulating ROS production, which is induced by CK2 inhibition. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |