Title : Novel mechanisms and signaling pathways of esophageal ulcer healing: the role of prostaglandin EP2 receptors, cAMP, and pCREB.

Pub. Date : 2014 Sep 15

PMID : 25059824






1 Functional Relationships(s)
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1 Treatment of rats with misoprostol, a PGE1 analog capable of activating EP receptors, enhanced phosphorylation of CREB, stimulated VEGF expression and angiogenesis, and accelerated esophageal ulcer healing. Misoprostol cAMP responsive element binding protein 1 Rattus norvegicus