Title : Liposomal nitrooxy-doxorubicin: one step over caelyx in drug-resistant human cancer cells.

Pub. Date : 2014 Sep 2

PMID : 25057799






1 Functional Relationships(s)
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1 This event was accompanied in parallel by a higher release of NO, which caused nitration of P-glycoprotein (Pgp) and multidrug resistance related protein 1 (MRP1), two transporters involved in Dox efflux, and impaired their pump activity. Doxorubicin ATP binding cassette subfamily C member 1 Homo sapiens