Pub. Date : 2014 Dec
PMID : 25056964
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tranexamic acid suppresses ultraviolet B eye irradiation-induced melanocyte activation by decreasing the levels of prohormone convertase 2 and alpha-melanocyte-stimulating hormone. | Tranexamic Acid | proopiomelanocortin | Homo sapiens |
| 2 | The plasma alpha-melanocyte-stimulating hormone (alpha-MSH) content was increased by UVB irradiation of the eye; however, the increase in alpha-MSH was suppressed by tranexamic acid treatment. | Tranexamic Acid | proopiomelanocortin | Homo sapiens |
| 3 | The plasma alpha-melanocyte-stimulating hormone (alpha-MSH) content was increased by UVB irradiation of the eye; however, the increase in alpha-MSH was suppressed by tranexamic acid treatment. | Tranexamic Acid | proopiomelanocortin | Homo sapiens |
| 4 | CONCLUSIONS: These results clearly indicate that tranexamic acid decreases the expression of PC2, which cleavages from proopiomelanocortin to alpha-MSH in the pituitary gland, thereby suppressing melanocyte activation. | Tranexamic Acid | proopiomelanocortin | Homo sapiens |