Pub. Date : 2014 Oct
PMID : 25048991
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NLRP3 inflammasome activation and interleukin-1beta release in macrophages require calcium but are independent of calcium-activated NADPH oxidases. | Calcium | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | OBJECTIVE AND DESIGN: We studied the involvement of calcium and calcium-activated NADPH oxidases in NLRP3 inflammasome activation and IL-1beta release to better understand inflammasome signaling in macrophages. | Calcium | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | TREATMENT: Murine or human macrophages were treated in vitro with NLRP3 inflammasome agonists (ATP, silica crystals) or calcium agonists (thapsigargin, ionomycin) in calcium-containing or calcium-free medium. | Calcium | NLR family pyrin domain containing 3 | Homo sapiens |
| 4 | TREATMENT: Murine or human macrophages were treated in vitro with NLRP3 inflammasome agonists (ATP, silica crystals) or calcium agonists (thapsigargin, ionomycin) in calcium-containing or calcium-free medium. | Calcium | NLR family pyrin domain containing 3 | Homo sapiens |