Title : Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: control on nuclear factor-κB signaling in consolidation and reconsolidation.

Pub. Date : 2014 Dec

PMID : 25043904






3 Functional Relationships(s)
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1 Accordingly, the inhibition of CaN by FK506 increased NF-kappaB activity in dorsal hippocampus. Tacrolimus nuclear factor kappa B subunit 1 Homo sapiens
2 The administration of the NF-kappaB signaling pathway inhibitor sulfasalazine (SSZ) impeded the enhancing effect of FK506. Tacrolimus nuclear factor kappa B subunit 1 Homo sapiens
3 The coadministration of SSZ and FK506 blocked the enhancement effect in reconsolidation, suggesting that this facilitation is also dependent on the NF-kappaB signaling pathway. Tacrolimus nuclear factor kappa B subunit 1 Homo sapiens