Pub. Date : 2014 Sep
PMID : 25040039
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effects of the novel SHIP1 activator AQX-1125 on allergen-induced responses in mild-to-moderate asthma. | 4-(4-(aminomethyl)-7a-methyl-1-methylideneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol | inositol polyphosphate-5-phosphatase D | Homo sapiens |
| 2 | AQX-1125 is a first-in-class, oral SHIP1 activator with a novel anti-inflammatory mode of action. | 4-(4-(aminomethyl)-7a-methyl-1-methylideneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol | inositol polyphosphate-5-phosphatase D | Homo sapiens |
| 3 | CONCLUSION AND CLINICAL RELEVANCE: AQX-1125, a novel oral SHIP1 activator, significantly reduces the late response to allergen challenge, with a trend to reduce airway inflammation. | 4-(4-(aminomethyl)-7a-methyl-1-methylideneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol | inositol polyphosphate-5-phosphatase D | Homo sapiens |