Title : Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation.

Pub. Date : 2014

PMID : 25033286






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Up-regulated sirtuin 1 (SIRT1), an NAD+-dependent class III histone deacetylase, deacetylates p53 and inhibits its transcriptional activity, leading to cell survival. NAD tumor protein p53 Homo sapiens