Title : Renin-angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma.

Pub. Date : 2014 Jul 17

PMID : 25032856






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The orally active AT1-R antagonist candesartan suppressed TLR4 and lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) expressions in the EAAC1 KO mouse retina. candesartan toll-like receptor 4 Mus musculus
2 In cultured Muller glia, candesartan suppressed LPS-induced iNOS production by inhibiting the TLR4-apoptosis signal-regulating kinase 1 pathway. candesartan toll-like receptor 4 Mus musculus