Title : Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis.

Pub. Date : 2014 Jul 29

PMID : 25024195






1 Functional Relationships(s)
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1 Prostaglandins derived from the cyclooxygenase (COX) pathway and epoxyeicosatrienoic acids (EETs) from the cytochrome P450/soluble epoxide hydrolase (sEH) pathway are important eicosanoids that regulate angiogenesis and tumorigenesis. eets cytochrome P450 family 4 subfamily F member 3 Homo sapiens