Title : Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress.

Pub. Date : 2014

PMID : 25019091






2 Functional Relationships(s)
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1 The elevated levels of both NADH and ROS can inhibit and inactivate glyceraldehyde 3-phosphate dehydrogenase (GAPDH), respectively, resulting in blockage of the glycolytic pathway and accumulation of glycerol 3-phospate and its prior metabolites along the pathway. Reactive Oxygen Species glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
2 The elevated levels of both NADH and ROS can inhibit and inactivate glyceraldehyde 3-phosphate dehydrogenase (GAPDH), respectively, resulting in blockage of the glycolytic pathway and accumulation of glycerol 3-phospate and its prior metabolites along the pathway. Reactive Oxygen Species glyceraldehyde-3-phosphate dehydrogenase Homo sapiens