Title : Thioridazine specifically sensitizes drug-resistant cancer cells through highly increase in apoptosis and P-gp inhibition.

Pub. Date : 2014 Oct

PMID : 24989930






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Thioridazine specifically sensitizes drug-resistant cancer cells through highly increase in apoptosis and P-gp inhibition. Thioridazine ATP binding cassette subfamily B member 1 Homo sapiens
2 THIO could also inhibit p-glycoprotein (P-gp) activity in the resistant KBV20C cells. Thioridazine ATP binding cassette subfamily B member 1 Homo sapiens
3 THIO could also inhibit p-glycoprotein (P-gp) activity in the resistant KBV20C cells. Thioridazine ATP binding cassette subfamily B member 1 Homo sapiens
4 As observed in a single treatment with THIO, the sensitization mechanism induced by the co-treatment also involves both apoptosis and P-gp inhibition. Thioridazine ATP binding cassette subfamily B member 1 Homo sapiens