Title : Involvement of glutathione peroxidase activity in the stimulation of 5-lipoxygenase activity by glutathione-depleting agents in human polymorphonuclear leukocytes.

Pub. Date : 1989 Apr 1

PMID : 2496978






1 Functional Relationships(s)
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1 Also, since co-incubation of fatty acid hydroperoxides with arachidonate caused activation of 5-lipoxygenase, we propose that Dnp-C1 increases the peroxide level in PMN which is required for the onset of lipoxygenase activity. Lipid Peroxides arachidonate 5-lipoxygenase Homo sapiens