Title : Selective estrogen receptor alpha agonist GTx-758 decreases testosterone with reduced side effects of androgen deprivation therapy in men with advanced prostate cancer.

Pub. Date : 2015 Feb

PMID : 24968970






2 Functional Relationships(s)
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1 Selective estrogen receptor alpha agonist GTx-758 decreases testosterone with reduced side effects of androgen deprivation therapy in men with advanced prostate cancer. Testosterone estrogen receptor 1 Homo sapiens
2 OBJECTIVE: To assess the ability of an oral selective estrogen receptor alpha agonist (GTx-758) to lower testosterone concentrations compared with leuprolide while minimizing estrogen deficiency-related side effects of androgen-deprivation therapy. Testosterone estrogen receptor 1 Homo sapiens