Title : Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-κB.

Pub. Date : 2014

PMID : 24966921






1 Functional Relationships(s)
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1 Pretreatment with diosmetin significantly reduced serum levels of amylase and lipase; the histological injury; the secretion of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6; myeloperoxidase (MPO) activity, trypsinogen activation peptide (TAP) level, the expression of inducible nitric oxide synthase (iNOS); and the nuclear factor (NF)-kappaB activation in cerulein-induced AP. diosmetin interleukin 6 Mus musculus