Title : Verrucarin A induces apoptosis through ROS-mediated EGFR/MAPK/Akt signaling pathways in MDA-MB-231 breast cancer cells.

Pub. Date : 2014 Nov

PMID : 24963595






1 Functional Relationships(s)
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1 Collectively, these results indicate that VA-induces ROS elevation in cancer cells, which results in the activation of p38MAPK and inhibition of EGFR/Akt/ERK signaling cascade and, ultimately, cancer cell death. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens