Title : The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

Pub. Date : 1989 Jan

PMID : 2496006






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 One instability determinant, which is located within the c-fos 3"-untranslated region, is a 75-nucleotide AU-rich segment. Gold Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 Nevertheless, specific deletion of the AU-rich element from c-fos mRNA has little effect on the transcript"s cytoplasmic half-life due to the presence of the other c-fos instability determinant, which is located in the protein-coding segment of the c-fos message. Gold Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens