Title : Gα13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration.

Pub. Date : 2014 Sep

PMID : 24958816






1 Functional Relationships(s)
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1 We also demonstrate that postsynaptic density 95/disk-large/ZO-1 (PDZ)-RhoGEF (PRG), a member of regulator of G-protein signaling (RGS)-homology domain (RH) containing guanine nucleotide exchange factors (RH-RhoGEFs), is the predominant activator of RhoA downstream of GRPR. Guanine Nucleotides Rho guanine nucleotide exchange factor 11 Homo sapiens