Pub. Date : 2014 Sep 15
PMID : 24958106
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PI3K catalyzes formation of phosphatidylinositol 3,4,5-triphosphate [PI(3,4,5)P3] after cell activation; PTEN subsequently reduces these lipids to basal levels. | phosphoinositide-3,4,5-triphosphate | phosphatase and tensin homolog | Homo sapiens |
| 2 | Our results show that PI3Ks dimerize in vivo and that PI3K and PTEN activities modulate each other in a complex that controls cell PI(3,4,5)P3 levels. | phosphoinositide-3,4,5-triphosphate | phosphatase and tensin homolog | Homo sapiens |