Title : Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway.

Pub. Date : 2014 Aug 8

PMID : 24951586






2 Functional Relationships(s)
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1 First, silencing ASM with siRNA abrogated IL-6 production in response to the tumor promoter, 4beta-phorbol 12-myristate 13-acetate (PMA), in MCF-7 cells, in distinction to acid beta-glucosidase 1 and acid ceramidase, suggesting specialization of the pathways. Tetradecanoylphorbol Acetate interleukin 6 Homo sapiens
2 First, silencing ASM with siRNA abrogated IL-6 production in response to the tumor promoter, 4beta-phorbol 12-myristate 13-acetate (PMA), in MCF-7 cells, in distinction to acid beta-glucosidase 1 and acid ceramidase, suggesting specialization of the pathways. Tetradecanoylphorbol Acetate interleukin 6 Homo sapiens